A. When used as a natural remedy for kidney stones it goes by the popular name of "stone breaker". Chanca Piedra is the Spanish name given to the herb Phyllanthus nirur i that is native to the Amazonian region of South America. Because little is known about chanca piedra, you should consult a healthcare provider before giving the supplement to children or adolescents. J Ethnopharmacol. Milk Thistle, Artichoke, Chanca Piedra, Dandelion & More! Posted 6/20/14. 2014;9(4):515-7. Biol.Pharm.Bull. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare providers because of something you have read on SelfHacked. J Urol. Take one to two servings before meals . J Urol. Ibrahim D, Hong LS, Kuppan N. Antimicrobial activity of crude methanolic extract from Phyllanthus niruri. View abstract. Koay YH, Basiri A, Murugaiyah V, et al. Lancet 10-1-1988;2(8614):764-766. Increasing appetite. View abstract. Amariinic acid and related ellagitannins from Phyllanthus amarus. 7-23-2008;118(2):318-323. But it also slows the accumulation of biliary sludge . Research Journal of Pharmaceutical Biological and Chemical Sciences 2010;335-340. To sum it up, chanca piedra may fight incredibly diverse types of infections. Pathophysiology. 2012;18(31):4162-6168. www.ars-grin.gov/duke (Accessed 3 November 1999). 2009;66(4):439-444. It can also stimulate the liver's bile secretion, thus helping the digestive process and the absorption of nutrients in the body. 2002;89(9):829-834. More human studies are needed to assess the effects of chanca piedra on liver health. Consult a healthcare professional before you use chanca piedra if you are taking medication. Ann.Trop.Med Parasitol. 2008;46(8):2658-2664. Indian J Biochem Biophys. Be sure to consult a healthcare provider if you have any concerns about chanca piedra and pregnancy or breastfeeding. Londhe, J. S., Devasagayam, T. P., Foo, L. Y., and Ghaskadbi, S. S. Antioxidant activity of some polyphenol constituents of the medicinal plant Phyllanthus amarus Linn. Celia A, Micali S Sighinolfi M et al. on aflatoxin B 1-induced liver damage in mice. Their reviews do not represent the opinions of SelfHacked. Navarro M, Coussio J Hnatyszyn O et al. Since chanca piedra may reduce blood pressure, it may also increase the effects of blood pressure-lowering drugs [57, 58, 59]. In mice and rats, chanca piedra blocked cancer growth, reduced tumors and increased survival rates [124, 125, 126, 127, 128, 129, 130, 131, 132]. Naaz F, Javed A Abdin MZ. justuwait. Kiemer, A. K., Hartung, T., Huber, C., and Vollmar, A. M. Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway. A., Amole, O. O., and Adeneye, A. K. Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in mice. Blood disorders: Chanca Piedra has also been shown to thin the blood and may be unsafe for people with bleeding disorders. Vijayanand V, Nagarajan B Vasu K. Efficacy of Azadirachta indica and Phyllanthus amarus in experimental hepatitis in dogs. Nutrients 2018;10(8). N Z Med J 1994;107:243. One health benefit of chanca piedra is that its antioxidants may improve fasting blood sugar levels in certain animals. and Thonn. Food Chemistry 2009;1405-1412. A dry extract of Phyllanthus niruri protects normal cells and induces apoptosis in human liver carcinoma cells. It reduces stress-related pain. Wang XH, Li CQ Guo XB et al. There are also no reported withdrawal symptoms. Clearing this dissolved mixture of salts and minerals from kidney stones (uric acid, oxalate, Decreasing enzymes linked to liver damage (, De-blocking liver detox pathways; it blocks an enzyme that reverses the detoxifying process of, Increasing important antioxidant, detoxifying compounds (, Lowering key inflammatory cytokines, enzymes, and messengers (, Asthma and lung inflammation (bronchitis), 1 2 capsules (400 500 mg chanca piedra extract per capsule) daily between meals, 30 60 drops (chanca piedra extract), 3 times a day, 30 minutes before meals or 2 hours after meals. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1992;10-11. Antioxidant properties of the isolated flavonoids from the medicinal plant Phyllanthus niruri. J Ethnopharmacol. Because chanca piedra is not approved by the FDA for any conditions, there is no official dose. It should also not be taken while breastfeeding or by children due to the lack of safety data in these two populations. View abstract. Send me exclusive offers, unique gift ideas, and personalized tips for shopping and selling . View abstract. J Bodyw Mov Ther. Chanca piedra (Phyllanthus niruri) blocked an enzyme (5-reductase) involved in baldness and increased the animals hair growth. Traditional Medicine and Nutraceuticals, A proceedings of WOCMAP III: The Third World Congress on Medicinal and Aromatic Plants 2003; Woottisin, S., Hossain, R. Z., Yachantha, C., Sriboonlue, P., Ogawa, Y., and Saito, S. Effects of Orthosiphon grandiflorus, Hibiscus sabdariffa and Phyllanthus amarus extracts on risk factors for urinary calcium oxalate stones in rats. 2010;42(5):280-282. More research is needed to understand the effect of chanca piedra on blood sugar levels in humans. Chanca piedra reduced oxidative stress and lowered inflammation in rats, mice, and cell-based studies [142, 124, 143, 144, 140, 105, 84, 145, 146, 147]. However, theres little evidence that its effective. Kumar MS, Jaiprakash B Hukkeri VI. It has also been used for other conditions, such as liver issues, ulcers, diabetes control, blood pressure . Intestinal gas. It is also known its hepatoprotector effect on the Hepatitis type B, C, A, herpes, and HIV. George A, Udani JK, Yusof A. 1. However, more human studies are needed to determine the effects of chanca piedra on liver health. The herb possesses alkalizing qualities that could help prevent kidney stones and gallstones from developing. Agri Res Svc: Dr. Duke's phytochemical and ethnobotanical databases. Udupa AL, Sanjeeva Benegal A. Therefore, it's best to avoid it while pregnant, trying to get pregnant, or breastfeeding. Asian Journal of Experimental Sciences 2010; Bhattacharjee, R. and Sil, P. C. The protein fraction of Phyllanthus niruri plays a protective role against acetaminophen induced hepatic disorder via its antioxidant properties. 1993;40(1):53-58. Hepatoprotective effect of ethanolic extract of Phyllanthus amarus Schum. The herb has alkalizing properties that may help prevent gallstones and acidic kidney stones from forming. Myanmar Health Sciences Research Journal 2009;17-21. Chanca piedra contains a chemical that might reduce the effects of norepinephrine. View abstract. View abstract. J Ethnopharmacol. Because some other herbs in the Phyllanthus genus exhibit strong antiviral activity against hepatitis B potentially rivaling that of the antiviral medication interferon researchers theorize that chanca piedra may have similar effects (1). Its combination with anti-diabetes therapies (e.g. 2020;24(1):15-18. It also boosts antioxidant enzymes such as glutathione, catalase and superoxide dismutase. Berk, L., de Man, R. A., Schalm, S. W., Labadie, R. P., and Heijtink, R. A. Nat Prod Commun. Dissolve Existing Kidney Stones and Prevent Future Ones: Our bodies receive signals all the time, from the food we eat. Chanca piedra may be unsafe for pregnant women or those trying to become pregnant. View abstract. Failure of New Zealand hepatitis B carriers to respond to Phyllanthus amarus. I'm in desperate need of some digestive help . Clinic study on chronic HBV infection treated by Phyllanthus amarus. It can also help eliminate bodily waste. Footer Yes! According to some claims, chanca piedra may have several beneficial effects on different body systems. Clark BC, Georgekutty J, Berul CI. In traditional ayahuasca ceremonies, people often drink chanca piedra tea for its calming effects. This might increase the risk of blood pressure becoming too low. and Thonn.). 2009;8(3):254-260. AIDS Res Hum.Retroviruses 1992;8(11):1937-1944. View abstract. Cancer Detect.Prev. 7. Raphael, K. R., Sabu, M. C., and Kuttan, R. Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum & Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential. Chanca Piedra 100 caps, chanca piedra leaf, Organic Stone breaker, kidney Liver Calculos Renales chancapiedra herbal capsules !!! Wang LT, He Y Ren JW Jiang J et al. The antiviral properties and the dense antioxidant content can control liver damage. People with type 1 or type 2 diabetes should also use this supplement with caution, as it may decrease blood sugar levels. Faremi, T. Y., Suru, S. M., Fafunso, M. A., and Obioha, U. E. Hepatoprotective potentials of Phyllanthusamarus against ethanol-induced oxidative stress in rats. Urinary tract infections and pain and swelling (inflammation). 2010;36(6):657-64; discussion 664. Review. If the gallbladder doesn't empty completely, the remaining particles, like cholesterol or calcium salts, can start to thicken and become biliary. Patients with conditions such as diabetes, potassium levels, blood . View abstract. Chanca piedra has the ability to lower blood sugar levels. 3. Evaluation of hair growth promoting activity of Phyllanthus niruri. 1999;20(4):164-166. We understand that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. 2013;8(4):493-6. View abstract. The Cochrane Library 1993;(1). Additionally, chanca piedra may reduce blood sugar levels. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Thyagarajan, S. P., Thiruneelakantan, K., Subramanian, S., and Sundaravelu, T. In vitro inactivation of HBsAg by Eclipta alba Hassk and Phyllanthus niruri Linn. In mice and cells, chanca piedra inhibited the growth of various bacteria, fungi, and parasites, including those that cause malaria, snail fever, and infections of the urinary tract, bowel, stomach, blood and skin (Plasmodium species, Escherichia coli, Staphylococcus, Enterobacter, Bacillus, Salmonella, Streptococcus, Helicobacter pylori , Candida) [100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111]. Chanca Piedra or "stone breaker" is well known for successfully treating kidney stones - it's where the herb got its name. In clinical studies with over 200 people with kidney stones, chanca piedra (Phyllanthus niruri) reduced their kidney stones, helping to clear the minerals and salt deposits [21, 22, 23, 24, 25, 26]. Patel S, Sharma V, S Chauhan N, Thakur M, Dixit VK. Raphael, K. R. and Kuttan, R. Inhibition of experimental gastric lesion and inflammation by Phyllanthus amarus extract. View abstract. Nitnaware KM, Naik DG Nikam TD. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. 2009;8(2):190-194. Asian Pac.J Cancer Prev. Krithika, R. and Verma, R. J. Ameliorative potential of Phyllanthus amarus against carbon tetrachloride-induced hepatotoxicity. Cealan A, Coman RT, Simon V, et al. Hypoglycaemic effect of Phyllanthus niruri leaves in rabbits. J Med Assoc.Thai. U.S. Food and Drug Administration.Warning Letter: Herbs America, Inc. MARCS-CMS 545913.. View abstract. In animal studies, the antioxidants in chanca piedra have been able to improve fasting blood sugar levels, which can help with blood sugar management (1, 7). 2016;68(8):953-69. Spanish for "stone crusher", Chanca Piedra is a plant that is traditionally used as a diuretic to help relieve mild urinary tract infections. Amount: 90 vegetarian capsules . Chanca piedra, which means "stone breaker" in Spanish, is a small herb. Early research suggests that taking a combination of chanca piedra and black seed by mouth for 7 days relieves pain in people with sore throat and swollen tonsils. Likewise, if facing surgery, it is best to avoid taking Chanca Piedra. WebMD does not provide medical advice, diagnosis or treatment. Most users were impressed with chanca piedra, as they reported it dissolved their kidney stones or gallstones and relieved them from pain and discomfort. Adeneye, A. View abstract. Consult with your doctor if you have bleedingdisorders since Chanca Piedra may slow blood clotting. It isn't just for stones. chanca piedra dosage for cats. Lee, C. D., Ott, M., Thyagarajan, S. P., Shafritz, D. A., Burk, R. D., and Gupta, S. Phyllanthus amarus down-regulates hepatitis B virus mRNA transcription and replication. Chanca Piedra Herb: 1 - 2 tsp . Wei W, Li X, Wang K, Zheng Z, Zhou M. Lignans with anti-hepatitis B virus activities from Phyllanthus niruri L. Phytother Res. Purification and characterisation of a novel antioxidant protein molecule from Phyllanthus niruri. The term "Chanca Piedra" literally means "to break stone" which reflects its traditional use in treating kidney stones and gallstones. but is for informational and educational purposes alone. Indian J Med Res 1982;76 Suppl:124-130. Advanced Chanca Piedra Capsule (Get One Bottle 50ml Advanced Chanca Piedra Drops Free) 623 (623/count)643 (3% off) Save 7% with coupon. 4. Niu, J. View abstract. Afr.J Med Med Sci 2000;29(2):119-122. In the studies that have been done on chanca piedra, there doesnt appear to be any risks to stopping the supplement suddenly. . et Thonn. A. Braz J Med Biol Res 1984; 17:313-21. A prospective, randomised short term study [abstract no: 178] . Research suggests it may also protect the liver, fight infections, and lower oxidative stress and inflammation. Bagchi GD, Choudhuri PK Kumar S. Registration of a cultivar of the medicinal plant bhumyamalaki Phyllanthus amarus. Tona, L., Mesia, K., Ngimbi, N. P., Chrimwami, B., Okond'ahoka, Cimanga, K., De, Bruyne T., Apers, S., Hermans, N., Totte, J., Pieters, L., and Vlietinck, A. J. In-vivo antimalarial activity of Cassia occidentalis, Morinda morindoides and Phyllanthus niruri. Kidney stones, or renal calculi, are masses made of crystals. Size. et. View abstract. May phyllanthus niruri (Uriston®) affect the efficacy of ESWL on renal stones? While its name translates to stone breaker, this herb may also protect the liver, lower inflammation, help with diabetes, and combat infections. View abstract. While this effect can help manage hyperglycemia (high blood sugar) . SelfDecode does not treat, diagnose or cure any conditions, Indian J Exp Biol 1995; 33:861-4. Southeast Asian J Trop.Med Public Health 2007;38(4):609-615. Animal and Cell Research (Lack of Evidence). Chanca Piedra has been proven in scientific . In one human study, some of the reported side effects of chanca piedra supplementation included: Abdominal pain was by far the most common, with the others being much less commonly reported (3). Int J Clin Pharmacol.Ther 2008;46(6):295-306. However, these 8 dietary strategies can help make sure you don't get another one. Harikrishnan H, Jantan I, Haque MA, Kumolosasi E. Anti-inflammatory effects of Phyllanthus amarus Schum. Narendranathan M, Mini PC Remla A. Subsequently, it delays sugar absorption and may prevent spikes in sugar levels after a meal. Align your health hacks with your genes for optimal health & cognitive function. World J Gastroenterol. 2005;68(4):537-539. View abstract. Chanca Piedra. If you choose to take chanca piedra, you should buy a supplement that has been independently verified for quality by a third party organization. Musuamba CT, Cimanga RK Dooghe L et al. Generally, if you are pregnant, nursing, have any health condition or are taking any medications, it is recommended that you consult your health care professional before using herbs, including culinary herbs. View abstract. 8 Natural Remedies to Fight Kidney Stones at Home, Stomach Ulcers and What You Can Do About Them, 14 Easy Ways to Lower Blood Sugar Levels Naturally. Common home remedies for kidney stones include drinking different fluids to help flush your stones out and prevent new ones. The English translation for Chanca piedra is stone crusher.' Recent scientific evidence validates this historical use. View abstract. View abstract. Increasing urine output. This item Chanca Piedra 1600 mg - 120 Tablets Kidney Stone Crusher Gallbladder Support Peruvian Chanca Piedra Made in The USA Stone Breaker Chanca Piedra - Natural Kidney Cleanse & Gallbladder Formula - Detoxify Urinary Tract, Flush Impurities, Clear System - Hydrangea & Celery Seed Extract - 60 Vegetarian Soft Capsules Chatterjee, M. and Sil, P. C. Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. It may also slow blood clotting and increase your risk of bleeding. Diabetics should consult their doctor before taking this plant as insulin medications may need monitoring and adjusting. . A study of the effect of Phyllanthus amarus extracts on blood glucose in rabbits. Trop.Gastroenterol. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. View abstract. View abstract. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. CHANCA PIEDRA ALSO KNOWN AS "STONE CRUSHER" FROM PLATNIUM NATURALS.Originally found growing in the Amazon rain forest, Chanca Piedra was named by the native Indians and noted for its ability to help dissolve kidney and gallstones. Phyllanthus amarus root clone with significant activity against bovine viral diarrhoea virus - a surrogate model of hepatitis C virus. View abstract. View abstract. . A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. Moreira J, Klein-Jnior LC, Cechinel Filho V, de Campos Buzzi F. Anti-hyperalgesic activity of corilagin, a tannin isolated from Phyllanthus niruri L. (Euphorbiaceae). Health of the digestive tract J Med Virol. Since there is no research on the long-term effects of chanca piedra, it may best to limit your intake of the herbal supplement to 12 weeks or fewer. We believe that the most accurate information is found directly in the scientific source. ( Read one of the studies.) Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Chanca piedra is an herb that grows in tropical areas mainly the rainforests of South America. Learn more. International Journal of Pharmacognosy 1997;35(3):167-173. Traditionally, this plant was used for abortions and may cause abnormalities with the fetus. Information is shared for educational purposes only. Diuretic activity of Phyllanthus niruri (Linn.) View abstract. Thidiazuron-induced shoot organogenesis and production of hepatoprotective lignan phyllanthin and hypophyllanthin in Phyllanthus amarus. Dirjomuljono, M., Kristyono, I., Tjandrawinata, R. R., and Nofiarny, D. Symptomatic treatment of acute tonsillo-pharyngitis patients with a combination of Nigella sativa and Phyllanthus niruri extract. There is evidence suggesting that chanca piedra may affect blood glucose levels. 2005;12(6-7):494-500. Taking chanca Piedra along with medications that also slow blood clotting might increase the risk of bruising and bleeding. J Med Virol. 1991;12(3):405-406. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. However, theres little research to support these claims. Zarzour RHA, Alshawsh MA, Asif M, et al. Chanca Piedra 500 mg Vegan Non-GMO Gluten-Free Supports a healthy liver An effective dose of a traditional remedy Promotes healthy kidneys and gallbladder Chanca Piedra is the Spanish name given to the herb Phyllanthus niruri which is native to the Amazonian region of South America. Doshi, J. C., Vaidya, A. J Ethnopharmacol. It enlarged blood vessels and caused kidney damage in rats and mice [159, 160, 161]. Huang ZR, Zhong JP, and Zhu GL. Healing and Rejuvenation: It's valued for its healing . 2013;146(1):318-23. Send me exclusive offers, unique gift ideas, and personalized tips for shopping and selling on . With the recent research demonstrating its ability to lower blood pressure and blood sugar, help treat diabetes, enhance liver health, and reduce the risk of developing disease . Food Chem Toxicol. View abstract. Foo LY. Be sure to consult a healthcare provider if you have any concerns about chanca piedra and pregnancy or breastfeeding. It's also purported to have anti-infection, anticancer, anti-inflammatory . Healthline Media does not provide medical advice, diagnosis, or treatment. J Nat Prod 1996;59:196-9. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Chitra R, Vadivel E Rajamani K. Estimation of anti-hepatic viral compounds in Phyllanthus amarus in vitro cultures. 2015;5(6):512-9. 2005-2023 Healthline Media a Red Ventures Company. 1993;41(4):275-281. Get it by Saturday, December 10. Chanca Piedra 800MG per Tablet - 120 Tablets Kidney Stone Crusher Gallbladder Support Peruvian Chanca Piedra Made in The USA. Chanca piedra has demonstrated hypoglycemic effects in animals and humans. View abstract. Rama Herbal Chanca Piedra Extract Tablets-60 Tablets Pack. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. But despite their efforts, few records of its folk use in the Amazonian region exist [8]. Moshi, M. J., Lutale, J. J., Rimoy, G. H., Abbas, Z. G., Josiah, R. M., and Swai, A. Raphael, K. R., Sabu, M., Kumar, K. H., and Kuttan, R. Inhibition of N-Methyl N'-nitro-N-nitrosoguanidine (MNNG) induced gastric carcinogenesis by Phyllanthus amarus extract. Odetola, A. Chanca Piedra is a medicinal herb believed to assist with various ailments related to the digestive system, liver, and kidneys. In one study in 56 people with kidney stones who took 4.5 grams of chanca piedra per day, researchers found that the kidney stones decreased in size and number in about two-thirds of participants (3). Sowjanya K, Girish C, Bammigatti C, Prasanna Lakshmi NC. 2006;176(3):1020-1022. which enables users to obtain detailed information and reports based on their genome. Zhu FM, Zhang JQ Zhang XZ et al. 2016;88(3):171-176. View abstract. One species of chanca piedra Phyllanthus niruri is safe and non-toxic. As an herbal medicine, chanca piedra is believed to be effective in treating various conditions of several body systems. Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Nishiura, J. L., Campos, A. H., Boim, M. A., Heilberg, I. P., and Schor, N. Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients. African Journal of Biotechnology 2010;248-259. View abstract. In a clinical study of 30 children with viral diarrhea, chanca piedra (Phyllanthus niruri) improved symptoms such as stool consistency, fever, vomiting, stomach pain, loss of appetite, and dehydration. 2-8-1999;136(1):11-16. 2008;13(5):199-207. Based on the available evidence, this herb cannot be confidently recommended for most conditions. Pucci ND, Marchini GS, Mazzucchi E, et al. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. A randomized, prospective, long-term study. . Chanca piedra can be taken with or without food. Wongnawa M, Thaina P Bumrungwong N et al. Abhyankar G, Suprasanna P Pandey BN et al. Plus, it contains some potential cancer-fighting compounds that have yet to be further explored [6, 1, 2, 7]. Growth inhibitory effects of Phyllanthus niruri extracts in combination with cisplatin on cancer cell lines. Indian J Pharmacol 2021;53(6):448-456. Chanca piedra (Gale of the wind) scientifically called ( Phyllanthus niruri L.) is a shrub-like herb from an annual tropical plant it is from the family Euphorb . Its scientific name is Phyllanthus niruri. Myint MM, Than MA Lwin KK et al. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. Asian Pac.J Trop.Med 2011;4(4):283-287. Asian Pac J Trop Med. All chanca piedra species are abundant in bioactive components, which carry their purported health benefits. They are a type of peptic ulcer disease. Boim, M. A., Heilberg, I. P., and Schor, N. Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. 2006;7(2):299-302. In rats and mice, chanca piedra had powerful lipid-balancing effects; it reduced total cholesterol, triglycerides, LDL cholesterol, VLDL cholesterol and increased HDL cholesterol. Phytochemistry 1995;39(1):217-224. Keep in mind that supplements arent regulated by any government organizations, so theres little oversight to ensure that the label is an honest representation of whats in the supplement. View abstract. Phytother.Res 2001;15(3):265-267. J Lab Clin Med 1995;126:350-2. View abstract. The uses below have been brought up in literature and are common in folk medicine, but there are no scientific studies about them [1, 5, 9, 10, 19, 157, 50]: Studies about the benefits of chanca piedra are limited; many are reviews and historical documents rather than clinical trials. When using it, monitor your blood sugar regularly if you have diabetes. Rao, M. V. and Alice, K. M. Contraceptive effects of Phyllanthus amarus in female mice. Some animal studies have shown a decrease in uric acid levels in animals receiving chanca piedra supplements (1). Hussain RA, Dickey JK Rosser MP et al. Jayaram, S. and Thyagarajan, S. P. Inhibition of HBsAg secretion from Alexander cell line by Phyllanthus amarus. Journal of Medicinal and Aromatic Plant Sciences 1999;21(1):51. View abstract. Actual . Comments 6 Comments . Notka, F., Meier, G., and Wagner, R. Concerted inhibitory activities of Phyllanthus amarus on HIV replication in vitro and ex vivo. A., and Odeku, O. 2002;82(1):19-22. Its important to note that most of the existing research on chanca piedra has been done in animals or test tubes, using highly concentrated extracts. Ajala, T. O., Igwilo, C. I., Oreagba, I. Both Phyllanthus niruri and P. amarus have been called chanca piedra. Its a less expensive, over-the-counter alternative to prescription potassium citrate, an alkalizing agent thats commonly used to prevent acidic kidney stones. Chanca piedra may work by blocking the enzymes that break down acetylcholine (acetylcholinesterase and butyrylcholinesterase). View abstract. Acta Pol.Pharm. The herb is believed to have health benefits in treating ulcers, urinary tract stones, and various conditions related to the kidneys, liver, and digestive system..

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